Formulation and Testing of SPF (Sun Protection Factor) Values of Nanoemulsion-Based Sunscreen Lotion from Raspberry (Rubus rosifolius Sm.) Fruit Extract

Authors

  • Syafira Salsa Biela Sekolah Tinggi Kesehatan Al-Fatah
  • Eka Putri Wiyati Sekolah Tinggi Kesehatan Al-Fatah
  • Gina Lestari Sekolah Tinggi Kesehatan Al-Fatah
  • Betna Dewi Sekolah Tinggi Kesehatan Al-Fatah

DOI:

https://doi.org/10.55606/ijmh.v5i3.6438

Keywords:

Nanoemulsion, Raspberry Fruit, SPF, Sunscreen Lotion, Rubus rosifolius Sm.

Abstract

Excessive exposure to ultraviolet radiation can cause skin damage, making the use of sunscreen necessary. Raspberry fruit (Rubus rosifolius Sm.) contains phenolic compounds, anthocyanins, and vitamin C, which have potential as natural antioxidants and active ingredients in sunscreen formulations. This study aimed to formulate raspberry fruit extract into a nanoemulsion, incorporate it into a sunscreen lotion formulation, and analyze the effect of different extract concentrations on SPF values. This experimental study used raspberry fruit extract obtained through maceration with 96% ethanol. The extract was formulated into a nanoemulsion using VCO, Tween 80, and PEG 400, and subsequently incorporated into lotion formulations at concentrations of 0% (F0), 10% (F1), 12.5% (F2), and 15% (F3). The nanoemulsion was evaluated based on organoleptic characteristics and particle size, while the lotion was evaluated for organoleptic characteristics, homogeneity, pH, spreadability, adhesion, viscosity, hedonic properties, and SPF value. The results showed that raspberry fruit extract was successfully formulated into a nanoemulsion with particle sizes ranging from 13.54 to 21.70 nm. All lotion formulations meet the physical quality requirements during four weeks of storage. The mean SPF values were 17,126 for F0, 17,666 for F1, 18,520 for F2, and 19,980 for F3. Statistical analysis showed that increasing the extract concentration had a significant effect on SPF values (p < 0.001). All formulations were classified as providing ultra protection, with F3 (15%) producing the highest SPF value and the most optimal UV protection.

References

Adha, MA, Saranani, S., & Andriani, R. (2025). Review Article: Liposome Ceramide Cream Formulation, Nyamplung, VCO and Glutathione as Sunscreen Moisturizer. Jurnal Mandala Pharmacon Indonesia (Jmpi), 11(1), 1–13.

Adhisa, S., & Megasari, DS (2020). Study of the Application of the True or False Type Cooperative Learning Model to Basic Competencies in Skin Disorders and Diseases. 09, 82–90.

Agustin, P. (2024). Nanoemulsion Formulation of a Combination of Sungkai Leaf Extract (Peronema Canescens Jack) and Cinnamon (Cinnamomum Burmannii (Nees & Th Nees) Blume) as an Antioxidant and Skin Protection Factor Agent.

Anwar, E. (2012). Excipients in Pharmaceutical Preparations : Characterization and Application. Dian Rakyat, Jakarta.

Arsyad, R., Amin, A., & Waris, R. (2023). Manufacturing Technique and Value of Simplicia and Ethanol Extract of Bagore Seeds (Caesalpinia Crist A L.) from Polewali Mandar. Makassar Natural Product Journal, 1(3), 138–147.

Athania, T., Purwati, E., Puspadina, V., & Safitri, CINH (2021). Formulation and Physical Quality Test of Pear Skin Extract Body Lotion (Pyrus Bretschneideri). 416–422.

Audrey, SI (2023). Utilization of Ethanol Extract of Secang Wood (Caesalpinia Sappan L.) and Strawberry Fruit (Fragaria Ananassa) as Sheet Mask Preparations.

Diah, Nurlaeli, L., & Nian, RB (2023). Formulation and Determination of SPF (Sun Protection Factor) Value of Torch Ginger Leaf Extract Lotion Preparation (Etlingera Elatior) In Vitro Using UV-Vis Spectrophotometry Method. Indonesian Scientific Journal of Pharmacy, 01(02), 12–22.

Dienilah, A. (2022). Formulation of Nanoemulsion Preparation of Strawberry Fruit Extract (Fragaria Sp) as an Active Ingredient in Making Antioxidant Serum.

Ermawati, DE, Rohmani, S., & Beandrade, MU (2023). Monograph Book of Nanoemulsion Systems for Cosmetic Preparations. Pt. Pena Persada Kerta Utama Editorial.

Fanshuri, B.., Agustina, D., Triasih, U., & Honestin, T. (2021). Indohits_Raspberry. In Researchgate (pp. 191–193).

Fathin, S., Qonitah, F., Ahwan, & Ariastuti, R. (2025). Test of the SPF (Sun Protection Factor) Value of Hand and Body Lotion Preparations with Ethanol Extract of Moringa Leaves. Pharmacy Medical Journal, 8(1), 31–39.

Fi Edition III. (1979). Department of Health of the Republic of Indonesia.

Fikri, MN, Bagiana, IK, & Cahyani, IM (2025). Formulation and Activity Test of SPF Value of Rambutan Leaf Ethanol Extract Lotion (Nephelium Lappaceum L.).

Halim, WCI, Mazidah, EN, Ghaliyah, TSR, & Najih, YA (2024). Formulation and Characterization of Nanoemulsion of 96% Ethanol Extract of Squid (Loligo Sp) and Virgin Coconut Oil. Journal of Herbal, Clinical and Pharmaceutical Sciences, 06(02).

Iskandar, B., Eni Sidabutar, SB, & Leny. (2021). Formulation And Evaluation Of Avocado Extract Lotion (Persea Americana) As A Skin Moisturizer. J. Islamic Pharm., 6(1), 14–21.

Jannah, SRN, Zubaydah, WOS, & Almunawarah, AAA (2025). Optimization of Kojic Acid Dipalmitate Nanoemulsion Preparation Using a Combination of Tween 80 and Peg 400 with Design-Expert. Lansau: Journal of Pharmaceutical Sciences (Ljik), 3(2), 102–115. https://Doi.Org/10.33772/Lansau.V3i2.47

Khairurrozikin, M. (2023). Formulation and Physical Evaluation of Blush On Stick from Ethanol Extract of Red Dragon Fruit (Hylocereus Polyrhizus).

Lanas, AF, Baharyati, D., & Meinisasti, R. (2024). Formulation of Sunscreen Hand Body Lotion from Ethanol Extract of Red Ginger Rhizome (Zingiber Officinale Var Rubrum Rhizoma) and SPF Value Test. Jurnal Pharmacopoeia, 3(1), 55–67.

Maslahah, N. (2024). Standards for Medicinal Plant Simplicia as Herbal Preparation Ingredients. 2(2), 1–4.

Maula, ADR, Fauziah, DT, Purwanti, A., & Agustin, AT (2025). Formulation and Evaluation of Hand Body Lotion Preparations from Avocado Seed Extract (Persea Americana Mill.). Journal of Pharmacy and Halal Studies (Jphs), 3(1), 11–22. https://Doi.Org/10.70608/6hahad10

Mubarok, F. (2021). Spectrophotometer Principles and How It Works. June.

Nurmalasari, DR, Yunita, RN, & Siddiq, HBHF (2023). Optimization of Ethanol Extract Concentration of Red Rose Flowers (Rosa Hybrida Hort.) on the Physical Properties of Sunscreen Lotion. Scientific Journal of Pharmacy, Academy of Pharmacy, 6(2), 8–15.

Pawarti, N., Iqbal, M., Ramdini, DA, & Yuliyanda, C. (2023). The Effect of Extraction Method on Percentage Yield and Phenolic Content of Plant Extracts with Potential as Antioxidants. 13(April), 590–593.

Qamariah, N., Handayani, R., & Mahendra, AI (2022). Hedonic Test and Storage Test of Ethanol Extract of Liver of Tanah Tubers Ointment. Surya Medika Journal (Jsm), 7(2), 124–131.

Rachmawati, P., Sagala, RJ, & Kambira, PFA (2021). Literature Review of Natural Sunscreen Dosage Forms, Safety and Effectiveness of Sunscreens. Review Article. 13, 25–39.

Raharjeng, SW, & Purwati, E. (2025). Formulation and Physical Quality Test of Body Lotion from Rambutan (Nephelium Lappaceum L.) Peel Extract. 7(1), 61–69.

Rahmasiaih, Hadiq, S., & Yulianti, T. (2023). Phytochemical Screening of Methanol Extract of Pandanus Amarillyfolius Roxb Leaves. 1(1), 33–39.

Riska Nafiah, S., Fitraneti, E., Rizal, Y., Primawati, I., & Hamama, DA (2024). The Effect of Ultraviolet Ray Exposure on Skin Health and Prevention Efforts. Scientific Journal, 3(3), 188–192. http://Journal.Scientic.Id/Index.Php/Sciena/Issue/View/19

Riyanto, & Haryanto, Y. (2023). The Effect of Extract Storage Length on Pinostrobin Levels in Temukunci (Kaemferia Pandurata, Roxb) Ethanol Extract. 2, 174–184.

Sari, EY, Mutia, C., Fitri, ZS, Sakhi, RATN, Maharini, I., & Elisma. (2025). Formulation of Nanoemulgel Preparation from Jernang Resin Extract (Daemonorops Draco (Wild.)) for Healing Burn Wounds in Male White Rats (Rattus Norvegicus). Jurnal Farmasimed (Jfm), 7(2), 371–380.

Sari, NT, Azkia, A., Prastyka, D., Tempati, JG, Syahjiah, L., Hasanah, M., Nadila, & Nita, RS (2025). Review Article: Comparison of Hot Extraction and Cold Extraction Methods. Journal of Innovation Research and Knowledge, 5(3), 3515–3528.

Taufiq, & Andriawan, AI (2025). Preparation and Physical Quality Testing of Jicama Starch (Pachyrhizus Erosus L.) Body Lotion Preparations. Yamasi Makassar Health Journal, 9(1), 123–131.

Ulfa, AM, Nofita, & Putri, AA (2025). Determination of the SPF Value of Butterfly Pea Flower Lotion (Clitoria Ternatea L.) Variation of VCO and Carrageenan as Sunscreen. Jurnal Medika Malahayati, 9(2).

Wiyati, EP, Alfitroh, I., Hardini, T., & Medianah, A. (2025). Screening of Flavonoids from Raspberry Juice (Rubus Idaeus L.) Using the Color Test Method. Journal of Education and Teaching Review, 8, 6764–6769.

Yuniarsih, N., Dinanti, D., Susanti, E.I., Latif, M.Z., Irma, R., Rades, R.A., Buana, U., Karawang, P., & Barat, J. (2023). Review Article: Body Lotion From Various Plant Extracts Review Article : Body Lotion From Various Plant Extracts. 6(2), 810 – 815.

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Published

2026-09-30

How to Cite

Syafira Salsa Biela, Eka Putri Wiyati, Gina Lestari, & Betna Dewi. (2026). Formulation and Testing of SPF (Sun Protection Factor) Values of Nanoemulsion-Based Sunscreen Lotion from Raspberry (Rubus rosifolius Sm.) Fruit Extract. International Journal of Medicine and Health, 5(3), 56–63. https://doi.org/10.55606/ijmh.v5i3.6438