Studi Toksikologi Biokimia : Dampak Senyawa Beracun Terhadap Proses Metabolisme Seluler dan Kesehatan Manusia
DOI:
https://doi.org/10.55606/sscj-amik.v3i2.5520Keywords:
Biochemical Toxicology, Cellular Metabolism, Toxic CompoundsAbstract
Biochemical toxicology studies are disciplines that study the impact of toxic compounds on biochemical processes in the human body. Toxic compounds, whether from the environment, industrial chemicals, drugs, or natural products, can interfere with cellular metabolic mechanisms and potentially cause damage to organs or body systems. This study aims to analyze how toxic compounds interact with biomolecules, such as proteins, enzymes, and nucleic acids, which play a role in cellular metabolic processes. Disruption of metabolic enzymes can affect key metabolic pathways, such as energy synthesis, detoxification, and homeostasis regulation. These toxic impacts can contribute to the development of acute and chronic diseases, including liver, kidney, nervous system disorders, and cancer. In this study, we also discuss the detoxification mechanisms involving enzymes such as cytochrome P450 and glutathione-S-transferase in reducing the toxic effects of these compounds. A deeper understanding of toxic interactions and their impact on cellular metabolism is essential in developing preventive and therapeutic strategies for poisoning or toxicity-related diseases. This research is expected to provide insight into the development of more effective drugs and medical approaches in overcoming the effects of toxic toxins on humans.
References
Abdullah, S. S., Putra, P. P., Antasionasti, I., Rundengan, G., Suoth, E. J., Abdullah, R. P. I., & Abdullah, F. (2022). Analisis sifat fisikokimia, farmakokinetik dan toksikologi pada pericarpium pala (Myristica fragransa) secara artificial intelligence. Chemistry Progress, 14(2), 81-92.
Hani'ah, U., Hernayanti, H., & Simanjuntak, S. B. I. (2020). Efek subletal limbah batik terhadap aktivitas enzim serum glutamat pyruvat transaminase pada serum ikan nila (Oreochromis niloticus). BioEksakta: Jurnal Ilmiah Biologi Unsoed, 2(1), 23-38.
Keman, S. (2020). Pengantar toksikologi lingkungan. Airlangga University Press.
Murdani, A. P., Tryanda, S. V. P., Melanie, R., Pati, D. U., Miranti, I. P., Drastyana, S. F., & Mardian, A. (2025). Pengantar toksikologi lingkungan. Sada Kurnia Pustaka.
Prahesti, N. A. (2023). Resensi buku petunjuk praktis aplikasi biomarker sederhana_1055.
Prihatiningsih, D. (2023). Toksikologi: Pengenalan terhadap toksin dan efeknya pada tubuh manusia. Wawasan Ilmu.
Rachman, R. M., Leda, J., Lorens, D., Putri, T. S., Saptaputra, S. K., & Mustika, W. (2024). Higiene dan toksikologi industri. TOHAR MEDIA.
Susanti, S. (n.d.). Buku ajar toksikologi pangan (ISBN: 978-623-417-091-7). Undip Press.
Yumni, G. G., Widyarini, S., & Fakhrudin, N. (2021). Kajian etnobotani, fitokimia, farmakologi dan toksikologi sukun (Artocarpus altilis (Park.) Fosberg). Jurnal Tumbuhan Obat Indonesia, 14(1), 55-70.
Additional Files
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Student Scientific Creativity Journal

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.